What are the interactions of Isosorbide Mononitrate ? 72% of reviewers reported a positive effect, while 12% reported a negative effect. If this worries you, talk to your doctor or pharmacist about other options. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. If you have any problems with the way your liver works, or any problems with the way your kidneys work. Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets; Merus Labs Luxco S.a.R.L, The electronic Medicines Compendium. The extended-release tablet usually is taken once daily in the morning. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Limit alcoholic beverages. Unless your doctor tells you otherwise, continue your normal diet. Does Alcohol Raise Your Blood Pressure? Should I avoid certain foods while taking Isosorbide Mononitrate? Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. Accessed Sept. 7, 2022. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. See also: aspirin side effects in more detail. Along with its needed effects, a medicine may cause some unwanted effects. amlodipine, lisinopril, aspirin, metoprolol, furosemide, carvedilol, propranolol, spironolactone, atenolol, diltiazem. It does not have such side effects. PMC Advertising revenue supports our not-for-profit mission. Some products have ingredients that could worsen your heart failure. This information is aggregated and used to produce personalized reports that patients can reference. Nitrates in the management of acute coronary syndrome. Do not take more or less of it or take it more often than prescribed by your doctor. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. In the remainder of them there was a highly significant time effect: the overall numbers of headache attacks in the first period of active treatment versus the second were 2,380 vs 1,400 (P < 0.003). Higher dosages are associated with stomach irritation and An official website of the United States government. Generic alternatives may be available. Isosorbide mononitrate helps to prevent angina chest pain from developing. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Does isosorbide mononitrate (Monoket) affect your kidneys? MeSH Mayo Clinic does not endorse companies or products. Isosorbide mononitrate (Monoket) can cause headaches, dizziness, or lightheadedness. Please note that only the generic name of each medication is listed below. It works by . URL of this page: https://medlineplus.gov/druginfo/meds/a682348.html. Sept. 26, 2022. isosorbide mononitrate (Rx) Brand and Other Names: Imdur, Monoket, more. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. Discuss the risks and benefits with your doctor. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). It works and leaves the body quickly, so it needs to be taken twice a day. If you suffer headaches when taking Isosorbide mononitrate, be patient. During pregnancy, this medication should be used only when clearly needed. This content does not have an Arabic version. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. Never give it to other people even if their condition appears to be the same as yours. Isosorbide mononitrate belongs to the group of medicines called nitrates. If you are having difficulty accessing this website, please call or email us at (855) 268-2822 or ada@goodrx.com so that we can provide you with the services you require through alternative means. FOIA Federal government websites often end in .gov or .mil. If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. Generic alternatives may be available. The authors assessed the occurrence of angina pectoris and headache by diary cards while taking into account the number of isosorbide dinitrate sublingual puffs and paracetamole tablets required. GoodRx works to make its website accessible to all, including those with disabilities. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. 67% of reviewers reported a positive effect, while 13% reported a negative effect. Continue to take isosorbide even if you feel well. Overview of herbal medicines and dietary supplements. Isosorbide controls chest pain but does not cure coronary artery disease. Once- versus twice-daily administration of controlled-release isosorbide-5-mononitrate 60 mg in the treatment of stable angina pectoris. Isosorbide mononitrate (Monoket) is available as both a immediate-release (IR, short-acting) and extended-release (ER, long-acting) tablet. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or to 30 mg 5-ISMN od for one week followed by 60 mg 5-ISMN od for one week. Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). This should pass after a few days. Isosorbide mononitrate works in two ways. tell your doctor if you are taking or have recently taken riociguat (Adempas) or a phosphodiesterase inhibitor (PDE-5) such as avanafil (Stendra), sildenafil (Revatio, Viagra), tadalafil (Adcirca, Cialis), and vardenafil (Levitra, Staxyn). Do not let anyone else take your medication. Let your provider know if they are excessive. Natural Medicines. (1) Starting on a low dosage was associated with a reduced frequency and severity of headache and did not notably influence the beneficial effect on angina pectoris. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. The information eHealthMe analyzes includes: Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. This risk may be even higher for certain groups. What You Need to Know, Angina (a specific type of chest pain) caused by heart disease. Anti-ischemic and anti-anginal effects of controlled-release and conventional isosorbide-5-mononitrate in stable angina pectoris. Side effects : headache, mild dizziness Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. In the US - Call your doctor for medical advice about side effects. No, that's not true all the time. Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure. health information, we will treat all of that information as protected health ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. Do not stop taking it without consulting your doctor. This document does not contain all possible drug interactions. Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls. And as many as 25% of people also take medicines ordered for them by their health care providers, also called prescription medicines. These side effects may go away during treatment as your body adjusts to the medicine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Contact your provider right away if you feel as if you are going to pass out and are experiencing an irregular heartbeat, nausea, vomiting, changes in vision, more sweating, or cold and clammy skin. Isosorbide mononitrate (Monoket) is not known to affect the kidneys. It is also important information to carry with you in case of emergencies. St. John's wort. Before It is particularly important that you tell your doctor if you are using any medicines to help treat erectile dysfunction. The extended-release tablet usually is taken once daily in the morning. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Daily headaches are a common side effect. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. Herbal medications in cardiovascular medicine. Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. Danshen can interact strongly with some heart medicines, such as: Evening primrose may raise your risk of bleeding if you also take a blood thinner, such as: Garlic may raise your risk of bleeding if you also take a blood thinner, such as: Ginkgo biloba may raise your risk of bleeding if you also take a blood thinner, such as: If you take ginseng with warfarin, it may lessen how well warfarin works. Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. https://naturalmedicines.therapeuticresearch.com. As precautionary measure, it is preferable to avoid the use of isosorbide mononitrate during pregnancy. Bauer B (expert opinion). Isosorbide mononitrate helps to prevent angina chest pain from developing. Ask your doctor before using aspirin together with alcohol. The longer you take isosorbide mononitrate, the more your body can become used to it (called tolerance), and then it can have less of an effect. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. information highlighted below and resubmit the form. flushing - try to cut down on coffee, tea and alcohol because they can make flushing worse. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. 55 ratings on Drugs.com. This branded product is no longer on the market. Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. Isosorbide mononitrate should not be used in patients with severe anaemia, severe hypotension, closed angle glaucoma or severe hypovolaemia.Isosorbide mononitrate may give rise to postural hypotension and syncope in some patients. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. If concomitant therapy cannot be avoided, monitor clinical effects of the . Breastfeeding:There is data that nitrates are excreted in breast milk and may cause methemoglobinemia in infants. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. This is called a medicine interaction. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips. Almost 70% of older adults use them. All rights reserved. It is unknown if this medication passes into breast milk. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. HHS Vulnerability Disclosure, Help View all It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. Each day, take the first dose when you wake up, then take the second dose 7 hours later. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Talk to your provider if you continue to feel dizzy or have a fast heart rate a week after starting isosorbide mononitrate (Monoket). Isosorbide mononitrate. Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. Isosorbide mononitrate (Monoket) is not a medication you take if you think you are having a heart attack. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. Call your doctor for medical advice about side effects. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. 7.6 out of 10 from a total of Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. Isosorbide is in a class of medications called vasodilators. All rights reserved. Your body can get used to isosorbide mononitrate (Monoket), and the same amount of medication might no longer work as well as it used to. Browse all drugs on eHealthMe. Methods: In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers.